UF scientists discover way to alter fentanyl, making the potent pain reliever safer

Scientists have discovered a way to alter the chemical properties of fentanyl, offering a safer alternative to the powerful pain reliever.

Fentanyl is a synthetic opioid similar to morphine but up to 100 times more potent. According to the Centers for Disease Control and Prevention, it is among the most abused pain relievers in the U.S. and the leading cause of overdose deaths. More than 80,000 Americans died from an opioid overdose in 2021.